منابع مشابه
Is A Universal, One Dose Cholera Vaccine Possible?
The Gram negative bacterium, Vibrio cholerae (Vc) causes cholera, an enteric disease that has killed untold numbers of humans. In the 19 th century, whole-cell (W-C) cholera vaccines were tested in humans. Field trials (1960s70s) of injected, killed W-C (kW-C) Vc showed cholera-specific immune responses (antibodies, Abs) could be induced with a single dose in certain cohorts, but more durable i...
متن کاملCorrection: The Impact of a One-Dose versus Two-Dose Oral Cholera Vaccine Regimen in Outbreak Settings: A Modeling Study.
Reference 1. Azman AS, Luquero FJ, Ciglenecki I, Grais RF, Sack DA, Lessler J (2015) The Impact of a One-Dose versus Two-Dose Oral Cholera Vaccine Regimen in Outbreak Settings: A Modeling Study. PLoSMed 12(8): e1001867. doi: 10.1371/journal.pmed.1001867 PMID: 26305226 Fig 4. Short-term protection from one and two doses of oral cholera vaccine.Reported estimates and results from random effects r...
متن کاملThe Impact of a One-Dose versus Two-Dose Oral Cholera Vaccine Regimen in Outbreak Settings: A Modeling Study
BACKGROUND In 2013, a stockpile of oral cholera vaccine (OCV) was created for use in outbreak response, but vaccine availability remains severely limited. Innovative strategies are needed to maximize the health impact and minimize the logistical barriers to using available vaccine. Here we ask under what conditions the use of one dose rather than the internationally licensed two-dose protocol m...
متن کامل"Bilivaccin-Cholera" versus Commercial Cholera Vaccine
2 died of natural causes before the experiment was completed. 1 died with 2 M. L,. D's. given on the 9th day after the last dose of vaccine. 1 died with 3 M. L,. D's. given on the 26th day after the last dose of vaccine. 1 died with 3 M. L,. D's. given on the 36th day after the last dose of vaccine. 3 survived with 2 M. L,. D's. given on the 44th, 22nd and 19th day, respectively, after the last...
متن کاملStockpiling oral cholera vaccine.
Editorials 714 Cholera is re-emerging as a threat on the global public health stage. The number of reported cases worldwide is back at the peak level observed two decades ago, 1 new Vibrio cholerae strains have appeared and antimicrobial resistance has increased. Weak surveillance systems and the possibility of travel and trade sanctions contribute to widespread underreporting of cholera cases,...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2012
ISSN: 0928-8244
DOI: 10.1111/j.1574-695x.2012.00993.x